leukotriene d 4 การใช้

One of their roles ( specifically, leukotriene D 4 ) is to trigger contractions in the smooth muscles lining the bronchioles; their overproduction is a major cause of inflammation in asthma and allergic rhinitis.
These enzymes hydrolyze a variety of dipeptides, including leukotriene D 4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine ( cys-bis-gly ) formed during glutathione degradation.
DPEP1 ( EC 3.4 . 13.11 ) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e . g ., leukotriene D 4 ( Kozak and Tate, 1982 ).
"' Ubenimex "'( leukotriene A 4 hydrolase ( a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities ), alanyl aminopeptidase ( aminopeptidase M / N ), leucyl / cystinyl aminopeptidase ( oxytocinase / vasopressinase ), and membrane dipeptidase ( leukotriene D 4 hydrolase ).